Providing resources and ideas for therapies and medical developments for Parkinson's disease:
This study included 7,130 people with head injury data.
Reference Association between Traumatic Brain Injury and Late Life Neurodegenerative Conditions and Neuropathological Findings
A study of more than 300,000 US veterans of which half were diagnosed with mild traumatic brain injury (TBI) due to explosions, found that more than 50% of them were at increased risk of developing Parkinson's disease even after adjusting for age and other demographics. Those more severely injured were associated with an even higher risk.
Reference Mild TBI and risk of Parkinson disease: A Chronic Effects of Neurotrauma Consortium Study
Parkinsonism is any condition which causes any of the movement disorders associated with Parkinson's Disease such as tremors, slow movement, impaired speech or stiff muscle movement. Parkinson's Disease is a single and a prevalent cause of Parkinsonism, but not the only cause. There are two forms of a stroke, an ischemic stroke which is caused by blood vessel blockage and hemorrhagic strokes caused by internal bleeding. About 87% of strokes are ischemic, the rest being hemorrhagic. Strokes including "small vessel strokes" can cause Vascular (Multi-Infarct) Parkinsonism by directly affecting the substantia nigra or the basal ganglia regions of the brain. Vascular Parkinsonism often involves the lower part of the body more than the upper part of the body and typically develops symptoms of parkinsonism on the opposite side of the body from the area of the brain affected. The blood vessel blockage is typically casued by:
The atherosclerotic blockage and lesions are composed of cellular material, blood vessle muscle, macrophages, lipid particles, cholesterol crystal, calcification, fibrous overgrowths and connective tissue.
Vascular health can be improved with Omega-3 and Niacin (vitamin B3) supplements. Studies have shown that the combination produced additive effects. Niacin reduces serum triglyceride (fat) levels and LDL (bad cholesterol) while raising HDL (good cholesterol). Omega-3 also reduces serum triglyceride levels and serves as an anti-coagulant. Omega-3 food sources include fish (choose low mercury, short lived, low on the food chain varieties like sardines, salmon, tilapia and avoid tuna, swordfish, shark) and avocados.
It has also been shown that vitamin D3 and K can improve vascular health. Vitamin D3 in combination with vitamin K can help with the absorption of calcium in the gut and remove calcium from the vascular compartment for storage in the bones, helping prevent osteoporosis and lowering the chance of stroke.
A statin like Lipitor can be added to lower cholesterol with a doctor's prescription. Low dose aspirin or prescription blood thinner can be added to avoid the coagulation of platelets which can block blood vessels. Anti-coagulants can only be used for ischemic strokes and will only worsen the condition of a hemorrhagic stroke. Also note that while aspirin is an over-the-counter medication, it can cause internal bleeding. Its misuse is not without consequences. In cases of extreme atherosclerosis, chelation with EDTA (specifically the NaMgEDTA variant which is preferred for targeting calcium and treating vascular disease ref) can clear out calcium deposits and plaque. Refer to the National Institute of Health (NIH) Trial to Assess Chelation Therapy (TACT) studies (ref). All medications should be taken under the guidance of a health professional.References:
Strokes can cause movement disorders which mimic Parkinson's and affect motor neurons but are treated as a stroke. Therapies include pharmalogical, electrical and physical therapies.Brief list of stroke rehabilitation therapies:
Magnetic Resonance Imaging (MRI) systems will have the capability to take a high resolution scan of the brain, revealing areas affected by stroke. MRIs can produce higher resolution images than Computed Tomography (CT) scans.
One can obtain a CD or DVD of the MRI images or datasets which can be viewed with viewing software included or with the Java based (runs on MS/Windows, Apple Mac, Linux) open source software Medical Image Processing, Analysis, and Visualization (MIPAV) developed by the US National Institutes of Health (NIH) Center for Information Technology (CIT).
MIPAV: point it to the top image directory on the DVD and select the "Parse Directory" icon, then just click on the various images to view them.